| Gene Information | |
|---|---|
| Gene Name | EDC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 508 |
| Protein Names | Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000179151 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q96F86 |
| Gene Card | EDC3 |
| Uniprot ID | Q96F86 |
| Pfam | PF09532; PF12701; PF03853 |
| In ASD | no |
| Allosteric Prediction | no (-0.795939717) |
| Ortholog in Animals | Alpaca_ EDC3 ( ortholog_one2one ) Dog_ EDC3 ( ortholog_one2one ) GuineaPig_ EDC3 ( ortholog_one2one ) Macaque_ EDC3 ( ortholog_one2one ) Mouse_ Edc3 ( ortholog_one2one ) Pig_ EDC3 ( ortholog_one2one ) Rat_ Edc3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland. {ECO:0000269|PubMed:17533573}. |
| Pharmacological Animal Models | 0.012047(Chimpanzee);0.028078(Mouse);0.007963(Rat);0.050000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2VC8 (X-ray 1.31A ) 2WAX (X-ray 2.30A ) 2WAY (X-ray 2.30A ) 3D3J (X-ray 2.80A ) 3D3K (X-ray 2.20A ) 6S8S (X-ray 2.21A ) |
| DBSNP | rs1057517676 |
| Subcellular location [CC] | Cytoplasm, P-body {ECO:0000269|PubMed:16364915}. Note=Processing bodies (PB). |
| Mouse PG classification | NA |
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