| Gene Information | |
|---|---|
| Gene Name | NOLC1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 699 |
| Protein Names | Nucleolar and coiled-body phosphoprotein 1 (140 kDa nucleolar phosphoprotein) (Nopp140) (Hepatitis C virus NS5A-transactivated protein 13) (HCV NS5A-transactivated protein 13) (Nucleolar 130 kDa protein) (Nucleolar phosphoprotein p130) |
| Target Name | nucleolar and coiled-body phosphoprotein 1 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000166197 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14978 |
| Gene Card | NOLC1 |
| Uniprot ID | Q14978 |
| Pfam | PF05022 |
| In ASD | no |
| Allosteric Prediction | no (-0.077240105) |
| Ortholog in Animals | Alpaca_ NOLC1 ( ortholog_one2one ) Dog_ NOLC1 ( ortholog_one2one ) GuineaPig_ NOLC1 ( ortholog_one2one ) Macaque_ NOLC1 ( ortholog_one2one ) Mouse_ Nolc1 ( ortholog_one2one ) Pig_ NOLC1 ( ortholog_one2one ) Rat_ Nolc1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);0.014815(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11191224 rs1049455 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:7657714}. Cytoplasm {ECO:0000269|PubMed:7657714}. Note=Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase. {ECO:0000269|PubMed:7657714}. |
| Mouse PG classification | NA |
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