| Gene Information | |
|---|---|
| Gene Name | GALNT6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 622 |
| Protein Names | Polypeptide N-acetylgalactosaminyltransferase 6 (EC 2.4.1.41) (Polypeptide GalNAc transferase 6) (GalNAc-T6) (pp-GaNTase 6) (Protein-UDP acetylgalactosaminyltransferase 6) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000139629 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NCL4 |
| Gene Card | GALNT6 |
| Uniprot ID | Q8NCL4 |
| Pfam | PF00535; PF00652 |
| In ASD | no |
| Allosteric Prediction | no (-0.735474793) |
| Ortholog in Animals | Alpaca_ GALNT6 ( ortholog_one2one ) Dog_ GALNT6 ( ortholog_one2one ) GuineaPig_ GALNT6 ( ortholog_one2one ) Macaque_ GALNT6 ( ortholog_one2one ) Mouse_ Galnt6 ( ortholog_one2one ) Pig_ GALNT6 ( ortholog_one2one ) Rat_ Galnt6 ( ortholog_one2one ) Rabbit_ GALNT6 ( ortholog_one2one ) |
| Ohnologs | GALNT3, GALNT12 |
| Paralogs | GALNT11, GALNT10, GALNTL6, GALNT1, GALNT16, GALNTL5, GALNT18, GALNT2, GALNT13, GALNT9, GALNT14, GALNT17, GALNT7, GALNT12, GALNT8, GALNT5, GALNT3, GALNT15, GALNT4 |
| Tissue | small.intestine |
| Tissue Specificity | Expressed in placenta and trachea. Weakly expressed in brain and pancreas. Expressed in fibroblast. Weakly or not expressed in lung, liver, muscle, kidney, spleen, thymus, prostate, testis, ovary, intestine, colon, leukocyte, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland and bone marrow. {ECO:0000269|PubMed:10464263}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs747300 |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000250|UniProtKB:Q14435}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q14435}. |
| Mouse PG classification | NA |
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