| Gene Information | |
|---|---|
| Gene Name | GALNT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 633 |
| Protein Names | Polypeptide N-acetylgalactosaminyltransferase 3 (EC 2.4.1.41) (Polypeptide GalNAc transferase 3) (GalNAc-T3) (pp-GaNTase 3) (Protein-UDP acetylgalactosaminyltransferase 3) (UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000115339 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q14435 |
| Gene Card | GALNT3 |
| Uniprot ID | Q14435 |
| Pfam | PF00535; PF00652 |
| In ASD | no |
| Allosteric Prediction | no (-0.333141771) |
| Ortholog in Animals | Alpaca_ GALNT3 ( ortholog_one2one ) Dog_ GALNT3 ( ortholog_one2one ) GuineaPig_ GALNT3 ( ortholog_one2one ) Macaque_ GALNT3 ( ortholog_one2one ) Mouse_ Galnt3 ( ortholog_one2one ) Pig_ GALNT3 ( ortholog_one2one ) Rat_ Galnt3 ( ortholog_one2one ) Rabbit_ GALNT3 ( ortholog_one2one ) |
| Ohnologs | GALNT12, GALNT6 |
| Paralogs | GALNT11, GALNT10, GALNTL6, GALNT1, GALNT16, GALNTL5, GALNT18, GALNT2, GALNT13, GALNT9, GALNT14, GALNT17, GALNT7, GALNT12, GALNT6, GALNT8, GALNT5, GALNT15, GALNT4 |
| Tissue | NA |
| Tissue Specificity | Expressed in organs that contain secretory epithelial glands. Highly expressed in pancreas, skin, kidney and testis. Weakly expressed in prostate, ovary, intestine and colon. Also expressed in placenta and lung and fetal lung and fetal kidney. {ECO:0000269|PubMed:12708471, ECO:0000269|PubMed:8663203}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane {ECO:0000269|PubMed:9394011}; Single-pass type II membrane protein {ECO:0000269|PubMed:9394011}. Note=Resides preferentially in the trans and medial parts of the Golgi stack. |
| Mouse PG classification | HPG |
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