| Gene Information | |
|---|---|
| Gene Name | FCHO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 810 |
| Protein Names | F-BAR domain only protein 2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000157107 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q0JRZ9 |
| Gene Card | FCHO2 |
| Uniprot ID | Q0JRZ9 |
| Pfam | PF00611; PF10291 |
| In ASD | no |
| Allosteric Prediction | yes (0.312663658) |
| Ortholog in Animals | Alpaca_ FCHO2 ( ortholog_one2one ) Dog_ FCHO2 ( ortholog_one2one ) GuineaPig_ FCHO2 ( ortholog_one2one ) Macaque_ FCHO2 ( ortholog_one2one ) Mouse_ Fcho2 ( ortholog_one2one ) Pig_ FCHO2 ( ortholog_one2one ) Rat_ Fcho2 ( ortholog_one2one ) Rabbit_ FCHO2 ( ortholog_one2one ) |
| Ohnologs | FCHO1, SGIP1 |
| Paralogs | PSTPIP2, SGIP1, PSTPIP1, GAS7, FCHO1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.099984(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2V0O (X-ray 2.30A ) 7OG1 (X-ray 3.25A ) 7OHO (X-ray 2.88A ) 7OHZ (X-ray 2.27A ) 7OI5 (X-ray 2.61A ) 7OIQ (X-ray 1.85A ) 7OIT (X-ray 1.65A ) |
| DBSNP | rs185435 |
| Subcellular location [CC] | Membrane, clathrin-coated pit {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Associated with forming but not mature clathrin-coated vesicles. The recruitment to coated-pits precede the one of clathrin and the adaptor protein complex AP-2 (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |