Gene Information
Gene NameGAL
OrganismHomo sapiens (Human)
Gene Length178
Protein NamesGerminal center-associated signaling and motility protein (Germinal center B-cell-expressed transcript 2 protein) (Germinal center-associated lymphoma protein) (hGAL)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000069482 )
Evolutionary StageVertebrata
AlphaFoldDBQ8N6F7
Gene CardGCSAM
Uniprot IDQ8N6F7
PfamPF15666
In ASDno
Allosteric Predictionyes (0.018910493)
Ortholog in AnimalsAlpaca_ GAL ( ortholog_one2one )
Dog_ GAL ( ortholog_one2many )
GuineaPig_ GAL ( ortholog_one2one )
Macaque_ GAL ( ortholog_one2one )
Mouse_ Gal ( ortholog_one2one )
Pig_ GAL ( ortholog_one2one )
Rat_ Gal ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissueappendix, pituitary.gland
Tissue SpecificityExpressed in diffuse large B-cell lymphoma (DLBCL) and several germinal center (GC)-like lymphoma cell lines (at protein level). Highly expressed in normal GC lymphocytes and GC-derived malignancies. Expressed in thymus and spleen. {ECO:0000269|PubMed:12509382, ECO:0000269|PubMed:12819018, ECO:0000269|PubMed:15677569}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cytoplasm. Cell membrane. Note=It relocalizes from the cytoplasm to podosome-like structures upon cell treatment with IL6.
Mouse PG classificationNA
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