| Gene Information | |
|---|---|
| Gene Name | PLAAT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 162 |
| Protein Names | Phospholipase A and acyltransferase 2 (EC 2.3.1.-) (EC 3.1.1.32) (EC 3.1.1.4) (HRAS-like suppressor 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000133328 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NWW9 |
| Gene Card | PLAAT2 |
| Uniprot ID | Q9NWW9 |
| Pfam | PF04970 |
| In ASD | no |
| Allosteric Prediction | no (-1.416098087) |
| Ortholog in Animals | Alpaca_ PLAAT2 ( ortholog_one2one ) GuineaPig_ PLAAT2 ( ortholog_one2one ) Macaque_ PLAAT3 ( ortholog_one2one ) Rabbit_ PLAAT2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PLAAT3, LRATD1, PLAAT4, LRATD2, PLAAT5, PLAAT1, LRAT |
| Tissue | duodenum, small.intestine, kidney |
| Tissue Specificity | Expressed in liver, kidney, small intestine testis and colon (PubMed:19615464). Undetectable in testis, placenta, salivary gland and fetal brain (PubMed:18163183). {ECO:0000269|PubMed:18163183, ECO:0000269|PubMed:19615464}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 4DPZ (X-ray 1.25A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18163183}. Membrane {ECO:0000255}; Single-pass membrane protein {ECO:0000255}. Note=Exhibits a granular pattern in the cytoplasm with preferential perinuclear localization. {ECO:0000269|PubMed:18163183}. |
| Mouse PG classification | NA |
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