Gene Information | |
---|---|
Gene Name | GADD45GIP1 |
Organism | Homo sapiens (Human) |
Gene Length | 222 |
Protein Names | Growth arrest and DNA damage-inducible proteins-interacting protein 1 (39S ribosomal protein L59, mitochondrial) (MRP-L59) (CKII beta-associating protein) (CR6-interacting factor 1) (CRIF1) (Mitochondrial large ribosomal subunit protein mL64) (Papillomavirus L2-interacting nuclear protein 1) (PLINP) (PLINP-1) (p53-responsive gene 6 protein) |
Target Name | NA |
Target Type | NA |
Gene Age | 645 ( ENSG00000179271 ) |
Evolutionary Stage | Eumetazoa |
AlphaFoldDB | Q8TAE8 |
Gene Card | GADD45GIP1 |
Uniprot ID | Q8TAE8 |
Pfam | PF10147 |
In ASD | no |
Allosteric Prediction | no (-0.887961072) |
Ortholog in Animals | Alpaca_ GADD45GIP1 ( ortholog_one2one ) Dog_ GADD45GIP1 ( ortholog_one2one ) GuineaPig_ GADD45GIP1 ( ortholog_one2one ) Macaque_ GADD45GIP1 ( ortholog_one2one ) Mouse_ Gadd45gip1 ( ortholog_one2one ) Pig_ GADD45GIP1 ( ortholog_one2one ) Rat_ Gadd45gip1 ( ortholog_one2one ) Rabbit_ GADD45GIP1 ( ortholog_one2one ) |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | Widely expressed. Highly expressed in the thyroid gland, heart, lymph nodes, trachea and adrenal tissues. Expressed at lower level in liver skeletal muscle, kidney, pancreas, testis, ovary and stomach. Barely detectable in adrenal adenoma and papillary thyroid cancer. {ECO:0000269|PubMed:12716909}. |
Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.174299(Rat);0.168337(Rabbit) |
Gene Ontology (biological process) |
|
Gene Ontology (cellular component) |
|
Gene Ontology (molecular function) |
|
PDB | 3J7Y (EM 3.40A ) 3J9M (EM 3.50A ) 5OOL (EM 3.06A ) 5OOM (EM 3.03A ) 6I9R (EM 3.90A ) 6NU2 (EM 3.90A ) 6NU3 (EM 4.40A ) 6VLZ (EM 2.97A ) 6VMI (EM 2.96A ) 6ZM5 (EM 2.89A ) 6ZM6 (EM 2.59A ) 6ZS9 (EM 4.00A ) 6ZSA (EM 4.00A ) 6ZSB (EM 4.50A ) 6ZSC (EM 3.50A ) 6ZSD (EM 3.70A ) 6ZSE (EM 5.00A ) 6ZSG (EM 4.00A ) 7A5F (EM 4.40A ) 7A5G (EM 4.33A ) 7A5H (EM 3.30A ) 7A5I (EM 3.70A ) 7A5J (EM 3.10A ) 7A5K (EM 3.70A ) 7L08 (EM 3.49A ) 7L20 (EM 3.15A ) 7O9K (EM 3.10A ) 7O9M (EM 2.50A ) 7ODR (EM 2.90A ) 7ODS (EM 3.10A ) 7ODT (EM 3.10A ) 7OF0 (EM 2.20A ) 7OF2 (EM 2.70A ) 7OF3 (EM 2.70A ) 7OF4 (EM 2.70A ) 7OF5 (EM 2.90A ) 7OF6 (EM 2.60A ) 7OF7 (EM 2.50A ) 7OG4 (EM 3.80A ) 7OI6 (EM 5.70A ) 7OI7 (EM 3.50A ) 7OI8 (EM 3.50A ) 7OI9 (EM 3.30A ) 7OIA (EM 3.20A ) 7OIB (EM 3.30A ) 7OIC (EM 3.10A ) 7OID (EM 3.70A ) 7OIE (EM 3.50A ) 7PD3 (EM 3.40A ) 7PO4 (EM 2.56A ) 7QH6 (EM 3.08A ) 7QH7 (EM 2.89A ) 7QI4 (EM 2.21A ) |
DBSNP | NA |
Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:22453275, ECO:0000269|PubMed:25278503, ECO:0000269|PubMed:25838379, ECO:0000269|PubMed:28892042}. Nucleus {ECO:0000269|PubMed:12482659}. Note=Using N-terminally tagged constructs, has been found in the nucleus (PubMed:12482659). C-terminally tagged constructs are targeted exclusively to mitochondria (PubMed:22453275). This discrepancy may be explained by masking of a potential N-terminal mitochondrial targeting signal by the tag (PubMed:22453275). {ECO:0000269|PubMed:12482659, ECO:0000269|PubMed:22453275}. |
Mouse PG classification | NA |
click here to return to the previous page |