| Gene Information | |
|---|---|
| Gene Name | GADD34 |
| Organism | Homo sapiens (Human) |
| Gene Length | 674 |
| Protein Names | Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O75807 |
| Gene Card | PPP1R15A |
| Uniprot ID | O75807 |
| Pfam | PF10488 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.05(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4XPN (X-ray 2.29A ) 7NXV (X-ray 2.55A ) 7NZM (EM 3.96A ) |
| DBSNP | rs564196 rs3786734 rs611251 rs557806 rs610308 rs11541192 rs556052 rs1050166 rs35087747 rs2270946 rs500079 |
| Subcellular location [CC] | Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side {ECO:0000269|PubMed:12556489, ECO:0000269|PubMed:21518769, ECO:0000269|PubMed:26742780}. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side {ECO:0000269|PubMed:21518769}. Note=Associates with membranes via an N-terminal amphipathic intramembrane region. {ECO:0000269|PubMed:21518769}. |
| Mouse PG classification | NA |
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