| Gene Information | |
|---|---|
| Gene Name | NKX2-2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 273 |
| Protein Names | Homeobox protein Nkx-2.2 (Homeobox protein NK-2 homolog B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000125820 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95096 |
| Gene Card | NKX2-2 |
| Uniprot ID | O95096 |
| Pfam | PF00046 |
| In ASD | no |
| Allosteric Prediction | no (-0.757382758) |
| Ortholog in Animals | Alpaca_ NKX2-2 ( ortholog_one2one ) Dog_ NKX2-2 ( ortholog_one2one ) GuineaPig_ NKX2-2 ( ortholog_one2one ) Mouse_ Nkx2-2 ( ortholog_one2one ) Pig_ NKX2-2 ( ortholog_one2one ) Rat_ Nkx2-2 ( ortholog_one2one ) Rabbit_ NKX2-2 ( ortholog_one2one ) |
| Ohnologs | NKX2-8 |
| Paralogs | NKX6-3, NKX2-8, NKX1-2, NKX2-1, NKX2-3, NKX6-1, NKX3-2, NKX1-1, NKX2-5, NKX6-2, NKX2-6, NKX2-4, NKX3-1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108}. |
| Mouse PG classification | NA |
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