| Gene Information | |
|---|---|
| Gene Name | GABRR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 465 |
| Protein Names | Gamma-aminobutyric acid receptor subunit rho-2 (GABA(A) receptor subunit rho-2) (GABA(C) receptor) |
| Target Name | gaba(a) receptor rho2 |
| Target Type | Literature-reported target |
| Gene Age | 544 ( ENSG00000111886 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P28476 |
| Gene Card | GABRR2 |
| Uniprot ID | P28476 |
| Pfam | PF02931; PF02932 |
| In ASD | no |
| Allosteric Prediction | yes (0.778708763) |
| Ortholog in Animals | Alpaca_ UBE2J1 ( ortholog_one2one ) Dog_ GABRR1 ( ortholog_one2one ) GuineaPig_ GABRR2 ( ortholog_one2one ) Macaque_ GABRR2 ( ortholog_one2one ) Mouse_ Gabrr2 ( ortholog_one2one ) Pig_ GABRR2 ( ortholog_one2one ) Rat_ Gabrr2 ( ortholog_one2one ) Rabbit_ GABRR2 ( ortholog_one2one ) |
| Ohnologs | GLRA2, GLRA4, GABRP |
| Paralogs | CHRNB1, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, GABRP, HTR3C, HTR3D, GABRG1, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, GABRA3, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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