| Gene Information | |
|---|---|
| Gene Name | GABRG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 467 |
| Protein Names | Gamma-aminobutyric acid receptor subunit gamma-3 (GABA(A) receptor subunit gamma-3) |
| Target Name | gaba(a) receptor benzodiazepine binding site |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000182256 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q99928 |
| Gene Card | GABRG3 |
| Uniprot ID | Q99928 |
| Pfam | PF02931; PF02932 |
| In ASD | no |
| Allosteric Prediction | yes (0.856630663) |
| Ortholog in Animals | Alpaca_ GABRG3 ( ortholog_one2one ) Dog_ GABRG3 ( ortholog_one2one ) Macaque_ GABRG3 ( ortholog_one2one ) Mouse_ Gabrg3 ( ortholog_one2one ) Pig_ GABRG3 ( ortholog_one2one ) Rat_ Gabrg3 ( ortholog_one2one ) Rabbit_ GABRG3 ( ortholog_one2one ) |
| Ohnologs | GABRE, GABRA1, GABRA4, GABRG2, GABRA6, GABRA2, GABRG1 |
| Paralogs | CHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRA2, GABRB3, GABRP, HTR3C, HTR3D, GABRG1, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, GABRA3, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2066712 |
| Subcellular location [CC] | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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