| Gene Information | |
|---|---|
| Gene Name | GABRD |
| Organism | Homo sapiens (Human) |
| Gene Length | 452 |
| Protein Names | Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta) |
| Target Name | gaba(a) receptor |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000187730 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14764 |
| Gene Card | GABRD |
| Uniprot ID | O14764 |
| Pfam | PF02931; PF02932 |
| In ASD | yes |
| Allosteric Prediction | yes (0.99994597) |
| Ortholog in Animals | Alpaca_ GABRD ( ortholog_one2one ) Dog_ GABRD ( ortholog_one2one ) GuineaPig_ GABRD ( ortholog_one2one ) Macaque_ GABRD ( ortholog_one2one ) Mouse_ Gabrd ( ortholog_one2one ) Pig_ GABRD ( ortholog_one2one ) Rat_ Gabrd ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, GABRP, HTR3C, HTR3D, GABRG1, CHRNA7, CHRFAM7A, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, GABRA3, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB |
| Tissue | brain, cerebral.cortex, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7QN5 (EM 2.50A ) 7QN6 (EM 2.90A ) 7QN7 (EM 3.00A ) 7QN8 (EM 3.10A ) 7QN9 (EM 2.90A ) 7QNC (EM 2.90A ) 7QND (EM 3.40A ) |
| DBSNP | rs121434580 rs139300921 rs41307846 rs1057519556 |
| Subcellular location [CC] | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | HPG |
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