| Gene Information | |
|---|---|
| Gene Name | GABRA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 492 |
| Protein Names | Gamma-aminobutyric acid receptor subunit alpha-3 (GABA(A) receptor subunit alpha-3) |
| Target Name | gaba(a) receptor alpha-3 |
| Target Type | Successful target |
| Gene Age | 544 ( ENSG00000011677 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P34903 |
| Gene Card | GABRA3 |
| Uniprot ID | P34903 |
| Pfam | PF02931; PF02932 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999953337) |
| Ortholog in Animals | Alpaca_ GABRA3 ( ortholog_one2one ) Alpaca_ GABRA3 ( ortholog_one2many ) Dog_ GABRA3 ( ortholog_one2one ) GuineaPig_ GABRA3 ( ortholog_one2one ) Macaque_ GABRA3 ( ortholog_one2one ) Mouse_ Gabra3 ( ortholog_one2one ) Pig_ GABRA3 ( ortholog_one2one ) Rat_ Gabra3 ( ortholog_one2one ) Rabbit_ GABRA3 ( ortholog_one2one ) |
| Ohnologs | GLRA4, GABRA1, GABRP, GABRA4, GLRB, GLRA3, GABRA6, GLRA1, GABRA2, GABRG1, GABRA5 |
| Paralogs | CHRNB1, GABRR2, CHRNA6, CHRNB4, CHRNA4, GABRQ, HTR3E, CHRNA1, CHRNA3, GABRA5, GLRA2, HTR3B, GLRA1, GABRG3, GABRA2, GABRB3, GABRP, HTR3C, HTR3D, GABRG1, CHRNA7, CHRFAM7A, GABRD, GABRR1, CHRNA5, GABRA6, GABRA4, GLRA3, GABRE, CHRNE, GABRG2, CHRND, CHRNA2, CHRNA10, CHRNA9, HTR3A, ZACN, CHRNB3, CHRNB2, CHRNG, GABRR3, GABRB2, GABRB1, GABRA1, GLRB |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |