| Gene Information | |
|---|---|
| Gene Name | GABARAPL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 117 |
| Protein Names | Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000034713 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P60520 |
| Gene Card | GABARAPL2 |
| Uniprot ID | P60520 |
| Pfam | PF02991 |
| In ASD | no |
| Allosteric Prediction | no (-0.215428798) |
| Ortholog in Animals | Alpaca_ GABARAPL2 ( ortholog_one2one ) Dog_ GABARAPL2 ( ortholog_one2one ) GuineaPig_ GABARAPL2 ( ortholog_one2one ) Macaque_ GABARAPL2 ( ortholog_one2one ) Mouse_ Gabarapl2 ( ortholog_one2one ) Rabbit_ GABARAPL2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAP1LC3C, GABARAPL1, GABARAP, MAP1LC3A, MAP1LC3B2, MAP1LC3B |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine. {ECO:0000269|PubMed:11146101, ECO:0000269|PubMed:11414770}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001253(Rat);0.019048(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4CO7 (X-ray 2.00A ) 6H8C (NMR - ) 7LK3 (X-ray 1.90A ) |
| DBSNP | rs11556291 |
| Subcellular location [CC] | Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:12507496, ECO:0000269|PubMed:15169837, ECO:0000269|PubMed:17580304, ECO:0000269|PubMed:19056683, ECO:0000269|PubMed:22311637, ECO:0000269|PubMed:31709703}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:30990354}. Golgi apparatus {ECO:0000250|UniProtKB:P60519}. |
| Mouse PG classification | NA |
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