| Gene Information | |
|---|---|
| Gene Name | G9A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1210 |
| Protein Names | Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Lysine N-methyltransferase 1C) (Protein G9a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96KQ7 |
| Gene Card | EHMT2 |
| Uniprot ID | Q96KQ7 |
| Pfam | PF12796; PF05033; PF00856 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined, with high levels in fetal liver, thymus, lymph node, spleen and peripheral blood leukocytes and lower level in bone marrow. {ECO:0000269|PubMed:11707778}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 2O8J (X-ray 1.80A ) 3DM1 (X-ray 2.40A ) 3K5K (X-ray 1.70A ) 3RJW (X-ray 2.56A ) 4NVQ (X-ray 2.03A ) 5JHN (X-ray 1.67A ) 5JIN (X-ray 1.85A ) 5JIY (X-ray 1.48A ) 5JJ0 (X-ray 1.72A ) 5T0K (X-ray 1.70A ) 5T0M (X-ray 1.90A ) 5TTF (X-ray 1.72A ) 5TUY (X-ray 2.60A ) 5V9I (X-ray 1.74A ) 5VSC (X-ray 1.40A ) 5VSE (X-ray 1.60A ) 6MM1 (X-ray 1.90A ) 7BTV (X-ray 2.00A ) 7BUC (X-ray 2.60A ) 7DCF (X-ray 1.80A ) 7T7L (X-ray 2.20A ) |
| DBSNP | rs7887 rs13919 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11316813}. Chromosome {ECO:0000269|PubMed:11316813}. Note=Associates with euchromatic regions. Does not associate with heterochromatin. |
| Mouse PG classification | NA |
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