| Gene Information | |
|---|---|
| Gene Name | G6PD |
| Organism | Homo sapiens (Human) |
| Gene Length | 515 |
| Protein Names | Glucose-6-phosphate 1-dehydrogenase (G6PD) (EC 1.1.1.49) |
| Target Name | glucose-6-phosphate 1-dehydrogenase |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000160211 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P11413 |
| Gene Card | G6PD |
| Uniprot ID | P11413 |
| Pfam | PF02781; PF00479 |
| In ASD | no |
| Allosteric Prediction | yes (1.575261705) |
| Ortholog in Animals | Alpaca_ G6PD ( ortholog_one2one ) Dog_ G6PD ( ortholog_one2one ) GuineaPig_ G6PD ( ortholog_one2one ) Macaque_ G6PD ( ortholog_one2one ) Mouse_ G6pdx ( ortholog_one2many ) Mouse_ G6pd2 ( ortholog_one2many ) Pig_ G6PD ( ortholog_one2one ) Rabbit_ G6PD ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | H6PD |
| Tissue | NA |
| Tissue Specificity | Isoform Long is found in lymphoblasts, granulocytes and sperm. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.021429(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1QKI (X-ray 3.00A ) 2BH9 (X-ray 2.50A ) 2BHL (X-ray 2.90A ) 5UKW (X-ray 2.65A ) 6E07 (X-ray 2.60A ) 6E08 (X-ray 1.90A ) 6JYU (X-ray 1.89A ) 6VA0 (X-ray 3.10A ) 6VA7 (X-ray 3.07A ) 6VA8 (X-ray 3.95A ) 6VA9 (X-ray 3.95A ) 6VAQ (X-ray 2.95A ) 7SEH (X-ray 2.90A ) 7SEI (X-ray 3.65A ) 7SNF (EM 3.40A ) 7SNG (EM 2.80A ) 7SNH (EM 2.20A ) 7SNI (EM 2.50A ) |
| DBSNP | rs137852340 rs78478128 rs76645461 rs137852315 rs1050828 rs137852349 rs138687036 rs782308266 rs267606835 rs1050829 rs78365220 rs137852341 rs137852313 rs137852314 rs137852331 rs5030872 rs267606836 rs782315572 rs5030868 rs137852330 rs137852332 rs137852332 rs782754619 rs137852326 rs137852319 rs137852328 rs137852328 rs137852318 rs74575103 rs137852327 rs137852339 rs137852347 rs76723693 rs5030869 rs137852342 rs137852333 rs137852329 rs137852322 rs137852320 rs137852334 rs137852321 rs137852316 rs137852335 rs1557229683 rs137852325 rs137852323 rs137852336 rs137852337 rs1557229599 rs137852317 rs398123546 rs137852324 rs72554665 rs72554665 rs72554664 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:743300}. Membrane; Peripheral membrane protein {ECO:0000269|PubMed:743300}. |
| Mouse PG classification | NA |
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