| Gene Information | |
|---|---|
| Gene Name | BCL9 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1426 |
| Protein Names | B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000116128 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O00512 |
| Gene Card | BCL9 |
| Uniprot ID | O00512 |
| Pfam | PF11502 |
| In ASD | no |
| Allosteric Prediction | yes (0.162065952) |
| Ortholog in Animals | Alpaca_ BCL9 ( ortholog_one2one ) Dog_ BCL9 ( ortholog_one2one ) GuineaPig_ BCL9 ( ortholog_one2one ) Macaque_ BCL9 ( ortholog_one2one ) Mouse_ Bcl9 ( ortholog_one2one ) Pig_ BCL9 ( ortholog_one2one ) Rat_ Bcl9 ( ortholog_one2one ) Rabbit_ BCL9 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BCL9L |
| Tissue | NA |
| Tissue Specificity | Detected at low levels in thymus, prostate, testis, ovary and small intestine, and at lower levels in spleen, colon and blood. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2GL7 (X-ray 2.60A ) 2VP7 (X-ray 1.65A ) 2VPB (X-ray 1.59A ) 2VPD (X-ray 2.77A ) 2VPE (X-ray 1.70A ) 2VPG (X-ray 1.60A ) 3SL9 (X-ray 2.20A ) |
| DBSNP | rs3820129 rs34002844 |
| Subcellular location [CC] | Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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