| Gene Information | |
|---|---|
| Gene Name | G3BP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 482 |
| Protein Names | Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000138757 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UN86 |
| Gene Card | G3BP2 |
| Uniprot ID | Q9UN86 |
| Pfam | PF02136; PF00076 |
| In ASD | no |
| Allosteric Prediction | no (-0.646820506) |
| Ortholog in Animals | Alpaca_ G3BP2 ( ortholog_one2one ) Dog_ G3BP2 ( ortholog_one2one ) GuineaPig_ G3BP2 ( ortholog_one2one ) Macaque_ G3BP2 ( ortholog_one2one ) Mouse_ G3bp2 ( ortholog_one2one ) Pig_ G3BP2 ( ortholog_one2one ) Rat_ G3bp2 ( ortholog_one2one ) Rabbit_ G3BP2 ( ortholog_one2one ) |
| Ohnologs | G3BP1 |
| Paralogs | G3BP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.01875(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5DRV (X-ray 2.75A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:23279204, ECO:0000269|PubMed:30404792}. Cytoplasm, Stress granule {ECO:0000269|PubMed:23279204, ECO:0000269|PubMed:30404792}. |
| Mouse PG classification | NA |
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