| Gene Information | |
|---|---|
| Gene Name | IL3RA |
| Organism | Homo sapiens (Human) |
| Gene Length | 378 |
| Protein Names | Interleukin-3 receptor subunit alpha (IL-3 receptor subunit alpha) (IL-3R subunit alpha) (IL-3R-alpha) (IL-3RA) (CD antigen CD123) |
| Target Name | interleukin 3 receptor alpha |
| Target Type | Successful target |
| Gene Age | 78 ( ENSG00000185291 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P26951 |
| Gene Card | IL3RA |
| Uniprot ID | P26951 |
| Pfam | PF18611; PF09240 |
| In ASD | no |
| Allosteric Prediction | no (-0.058490885) |
| Ortholog in Animals | Rat_ Il3ra ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CRLF1, IL13RA2, IL11RA, IL13RA1, CNTFR, IL2RG, CRLF2, IL31RA, IL6ST, IL12RB1, CSF3R, IL12RB2, GHR, CSF2RA, IL6R, IL27RA, IL23R, LIFR, OSMR, IL5RA, EBI3, PRLR, LEPR |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4JZJ (X-ray 2.80A ) 5UV8 (X-ray 2.70A ) 5UWC (X-ray 2.40A ) 6NMY (X-ray 3.30A ) |
| DBSNP | rs6647004 rs17886756 rs17883572 rs17883366 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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