| Gene Information | |
|---|---|
| Gene Name | FZD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 647 |
| Protein Names | Frizzled-1 (Fz-1) (hFz1) (FzE1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000157240 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UP38 |
| Gene Card | FZD1 |
| Uniprot ID | Q9UP38 |
| Pfam | PF01534; PF01392 |
| In ASD | no |
| Allosteric Prediction | yes (0.080187263) |
| Ortholog in Animals | Dog_ FZD1 ( ortholog_one2one ) GuineaPig_ FZD1 ( ortholog_one2one ) Mouse_ Fzd1 ( ortholog_one2one ) Pig_ FZD1 ( ortholog_one2one ) Rat_ Fzd1 ( ortholog_one2one ) Rabbit_ FZD1 ( ortholog_one2one ) |
| Ohnologs | FZD2, FZD7 |
| Paralogs | SFRP5, SFRP1, FZD5, FZD2, FZD10, FZD9, SFRP4, FZD7, FRZB, FZD6, FZD8, SMO, SFRP2, FZD4, FZD3 |
| Tissue | NA |
| Tissue Specificity | Expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. {ECO:0000269|PubMed:9813155}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3750146 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:10557084}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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