Gene Information
Gene NameFYR
OrganismHomo sapiens (Human)
Gene Length496
Protein NamesFizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9UM11
Gene CardFZR1
Uniprot IDQ9UM11
PfamPF12894; PF00400
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityIsoform 2 is expressed at high levels in heart, liver, spleen and some cancer cell lines whereas isoform 3 is expressed only at low levels in these tissues. {ECO:0000269|PubMed:12797865}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.357920(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4UI9  (EM  3.60A  5L9T  (EM  6.40A  5L9U  (EM  6.40A  7QE7  (EM  2.90A 
DBSNP NA 
Subcellular location [CC][Isoform 2]: Nucleus.;
[Isoform 3]: Cytoplasm.
Mouse PG classificationNA
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