| Gene Information | |
|---|---|
| Gene Name | FYB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 728 |
| Protein Names | FYN-binding protein 2 (Activation-dependent, raft-recruited ADAP-like phosphoprotein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000187889 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q5VWT5 |
| Gene Card | FYB2 |
| Uniprot ID | Q5VWT5 |
| Pfam | PF14603 |
| In ASD | no |
| Allosteric Prediction | no (-1.704211821) |
| Ortholog in Animals | Alpaca_ FYB2 ( ortholog_one2one ) GuineaPig_ FYB2 ( ortholog_one2one ) Macaque_ FYB2 ( ortholog_one2one ) Mouse_ Fyb2 ( ortholog_one2one ) Pig_ FYB2 ( ortholog_one2one ) Rat_ AABR07049499.1 ( ortholog_one2one ) Rabbit_ FYB2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FYB1, PRAM1 |
| Tissue | liver, oviduct |
| Tissue Specificity | Expressed in T-cells (at protein level). Widely expressed. {ECO:0000269|PubMed:27335501}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17114336 |
| Subcellular location [CC] | Membrane raft {ECO:0000269|PubMed:27335501}. Note=Recruited to membrane rafts and immunological synapse after TCR stimulation. {ECO:0000269|PubMed:27335501}. |
| Mouse PG classification | NA |
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