| Gene Information | |
|---|---|
| Gene Name | FUT8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 575 |
| Protein Names | Alpha-(1,6)-fucosyltransferase (Alpha1-6FucT) (EC 2.4.1.68) (Fucosyltransferase 8) (GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase) (GDP-fucose--glycoprotein fucosyltransferase) (Glycoprotein 6-alpha-L-fucosyltransferase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000033170 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9BYC5 |
| Gene Card | FUT8 |
| Uniprot ID | Q9BYC5 |
| Pfam | PF19745; PF14604 |
| In ASD | no |
| Allosteric Prediction | no (-0.60248476) |
| Ortholog in Animals | Alpaca_ FUT8 ( ortholog_one2one ) Dog_ FUT8 ( ortholog_one2one ) GuineaPig_ FUT8 ( ortholog_one2one ) Macaque_ FUT8 ( ortholog_one2one ) Mouse_ Fut8 ( ortholog_one2one ) Pig_ FUT8 ( ortholog_one2one ) Rat_ Fut8 ( ortholog_one2one ) Rabbit_ FUT8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DE0 (X-ray 2.61A ) 6VLD (X-ray 2.28A ) 6VLE (X-ray 2.28A ) 6X5H (X-ray 2.25A ) 6X5R (X-ray 2.40A ) 6X5S (X-ray 3.30A ) 6X5T (X-ray 2.47A ) 6X5U (X-ray 3.20A ) |
| DBSNP | rs2229678 rs35949016 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Note=Membrane-bound form in trans cisternae of Golgi. {ECO:0000250}. |
| Mouse PG classification | NA |
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