| Gene Information | |
|---|---|
| Gene Name | FUT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 530 |
| Protein Names | Alpha-(1,3)-fucosyltransferase 4 (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (ELAM-1 ligand fucosyltransferase) (Fucosyltransferase 4) (Fucosyltransferase IV) (Fuc-TIV) (FucT-IV) (Galactoside 3-L-fucosyltransferase) |
| Target Name | fucosyltransferase iv |
| Target Type | Successful target |
| Gene Age | 987 ( ENSG00000196371 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P22083 |
| Gene Card | FUT4 |
| Uniprot ID | P22083 |
| Pfam | PF17039; PF00852 |
| In ASD | no |
| Allosteric Prediction | no (-0.455533744) |
| Ortholog in Animals | Alpaca_ FUT4 ( ortholog_one2one ) Dog_ FUT4 ( ortholog_one2one ) GuineaPig_ FUT4 ( ortholog_one2one ) Mouse_ Fut4 ( ortholog_one2one ) Pig_ FUT4 ( ortholog_one2one ) Rat_ Fut4 ( ortholog_one2one ) Rabbit_ FUT4 ( ortholog_one2one ) |
| Ohnologs | FUT5, FUT6, FUT3, FUT9, FUT7 |
| Paralogs | FUT9, FUT11, FUT5, FUT3, FUT6, FUT7, FUT10 |
| Tissue | NA |
| Tissue Specificity | [Isoform Short]: Expressed at low levels in bone marrow-derived mesenchymal stem cells. {ECO:0000269|PubMed:29593094}.; Expressed in cord blood immature promyelocytes and in peripheral blood myeloid and lymphoid cell populations. {ECO:0000269|PubMed:11278338}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs2230273 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi. |
| Mouse PG classification | NA |
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