| Gene Information | |
|---|---|
| Gene Name | FUT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 361 |
| Protein Names | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3 (EC 2.4.1.65) (4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase) (EC 2.4.1.152) (Alpha-3-fucosyltransferase FUT3) (EC 2.4.1.-) (Blood group Lewis alpha-4-fucosyltransferase) (Lewis FT) (Fucosyltransferase 3) (Fucosyltransferase III) (FucT-III) |
| Target Name | galactoside 3(4)-l-fucosyltransferase |
| Target Type | Clinical trial target |
| Gene Age | 78 ( ENSG00000171124 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P21217 |
| Gene Card | FUT3 |
| Uniprot ID | P21217 |
| Pfam | PF17039; PF00852 |
| In ASD | no |
| Allosteric Prediction | no (-1.377592328) |
| Ortholog in Animals | Alpaca_ FUT3 ( ortholog_one2one ) |
| Ohnologs | FUT7, FUT4 |
| Paralogs | FUT9, FUT11, FUT4, FUT7, FUT10, FUT5, FUT6 |
| Tissue | appendix, cervix, colon, gall.bladder, seminal.vesicle, submandibular.gland, tongue, vas.deferens, zone.of.skin, sigmoid.colon, small.intestine, esophagus.mucosa, minor.salivary.gland, transverse.colon |
| Tissue Specificity | Highly expressed in stomach, colon, small intestine, lung and kidney and to a lesser extent in salivary gland, bladder, uterus and liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28362458 rs28362459 rs812936 rs59796499 rs778986 rs1175404919 rs28362462 rs28362463 rs3745635 rs28362466 rs28381968 rs28381969 rs28381970 rs151218854 rs3894326 |
| Subcellular location [CC] | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein {ECO:0000269|PubMed:1977660}. Note=Membrane-bound form in trans cisternae of Golgi. |
| Mouse PG classification | NA |
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