| Gene Information | |
|---|---|
| Gene Name | FUCA1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 466 |
| Protein Names | Tissue alpha-L-fucosidase (EC 3.2.1.51) (Alpha-L-fucosidase I) (Alpha-L-fucoside fucohydrolase 1) (Alpha-L-fucosidase 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000179163 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P04066 |
| Gene Card | FUCA1 |
| Uniprot ID | P04066 |
| Pfam | PF01120; PF16757 |
| In ASD | no |
| Allosteric Prediction | yes (0.063890375) |
| Ortholog in Animals | Alpaca_ FUCA1 ( ortholog_one2one ) Dog_ FUCA1 ( ortholog_one2one ) GuineaPig_ FUCA1 ( ortholog_one2one ) Macaque_ FUCA1 ( ortholog_one2one ) Mouse_ Fuca1 ( ortholog_one2one ) Pig_ FUCA1 ( ortholog_one2one ) Rat_ Fuca1 ( ortholog_one2one ) Rabbit_ FUCA1 ( ortholog_one2one ) |
| Ohnologs | FUCA2 |
| Paralogs | FUCA2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7PLS (EM 2.49A ) 7PM4 (EM 2.49A ) |
| DBSNP | rs2070955 rs2070956 rs1353778985 rs2228424 rs665 rs1126512 rs13551 rs80358199 |
| Subcellular location [CC] | Lysosome {ECO:0000269|PubMed:9741689}. |
| Mouse PG classification | NA |
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