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Gene Information
Gene Name
FTH1
Organism
Homo sapiens (Human)
Gene Length
183
Protein Names
Ferritin heavy chain (Ferritin H subunit) (EC 1.16.3.1) (Cell proliferation-inducing gene 15 protein) [Cleaved into: Ferritin heavy chain, N-terminally processed]
Target Name
ferritin
Target Type
Clinical trial target
Gene Age
70 ( ENSG00000167996 )
Evolutionary Stage
Cellular_organisms
AlphaFoldDB
P02794
Gene Card
FTH1
Uniprot ID
P02794
Pfam
PF00210
In ASD
no
Allosteric Prediction
yes (0.260013234)
Ortholog in Animals
Alpaca_ FTH1 ( ortholog_one2one )
GuineaPig_ FTH1 ( ortholog_one2one )
Macaque_ FTH1 ( ortholog_one2one )
Mouse_ Fth1 ( ortholog_one2one )
Ohnologs
FTL
Paralogs
FTMT, FTL, FTHL17
Tissue
NA
Tissue Specificity
Expressed in the liver. {ECO:0000269|PubMed:11389486}.
Pharmacological Animal Models
NA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
1FHA
(X-ray
2.40A
)
2CEI
(X-ray
1.80A
)
2CHI
(X-ray
1.60A
)
2CIH
(X-ray
1.50A
)
2CLU
(X-ray
2.10A
)
2CN6
(X-ray
2.20A
)
2CN7
(X-ray
1.75A
)
2FHA
(X-ray
1.90A
)
2IU2
(X-ray
1.80A
)
2Z6M
(X-ray
2.72A
)
3AJO
(X-ray
1.52A
)
3AJP
(X-ray
1.90A
)
3AJQ
(X-ray
1.58A
)
3ERZ
(X-ray
3.06A
)
3ES3
(X-ray
2.79A
)
4DYX
(X-ray
1.85A
)
4DYY
(X-ray
1.90A
)
4DYZ
(X-ray
2.30A
)
4DZ0
(X-ray
2.50A
)
4OYN
(X-ray
1.43A
)
4Y08
(X-ray
1.34A
)
4YKH
(X-ray
1.52A
)
4ZJK
(X-ray
1.56A
)
5CMQ
(X-ray
1.94A
)
5CMR
(X-ray
3.79A
)
5GN8
(X-ray
2.81A
)
5GOU
(X-ray
2.91A
)
5JKK
(X-ray
1.60A
)
5JKL
(X-ray
1.80A
)
5JKM
(X-ray
1.80A
)
5N26
(X-ray
2.05A
)
5N27
(X-ray
1.74A
)
5UP7
(X-ray
1.79A
)
5UP8
(X-ray
2.63A
)
5UP9
(X-ray
2.45A
)
5VTD
(X-ray
1.95A
)
5XB1
(EM
3.00A
)
5YI5
(EM
3.00A
)
5ZND
(X-ray
3.00A
)
6B8F
(X-ray
1.06A
)
6B8G
(X-ray
1.13A
)
6FTV
(X-ray
1.58A
)
6GSR
(EM
5.50A
)
6H5I
(EM
3.90A
)
6H6T
(X-ray
1.90A
)
6H6U
(X-ray
2.00A
)
6IPC
(X-ray
4.44A
)
6IPO
(X-ray
3.00A
)
6IPP
(X-ray
2.70A
)
6IPQ
(X-ray
3.10A
)
6J4A
(X-ray
3.99A
)
6J7G
(X-ray
3.87A
)
6JOB
(Other
2.93A
)
6JPS
(X-ray
3.50A
)
6KE2
(X-ray
1.80A
)
6KE4
(X-ray
2.30A
)
6M52
(EM
2.60A
)
6M54
(EM
2.40A
)
6WYF
(X-ray
1.25A
)
6WYG
(X-ray
2.27A
)
6WYH
(X-ray
2.22A
)
6Z6U
(EM
1.25A
)
6Z9E
(EM
1.55A
)
6Z9F
(EM
1.56A
)
7A6A
(EM
1.15A
)
7A6B
(EM
1.33A
)
7CK8
(X-ray
1.80A
)
7CK9
(X-ray
1.60A
)
7JGK
(X-ray
2.68A
)
7JGL
(X-ray
2.34A
)
7JGM
(X-ray
2.31A
)
7JGN
(X-ray
2.07A
)
7JGO
(X-ray
3.08A
)
7JGP
(X-ray
6.42A
)
7JGQ
(X-ray
3.01A
)
7K26
(X-ray
2.70A
)
7K3V
(EM
1.34A
)
7K3W
(EM
1.36A
)
7KE3
(X-ray
2.20A
)
7KE5
(X-ray
2.80A
)
7PF1
(EM
2.10A
)
7R5O
(EM
1.60A
)
7RRP
(EM
1.27A
)
7VD8
(EM
1.96A
)
DBSNP
NA
Subcellular location [CC]
NA
Mouse PG classification
NA
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