| Gene Information | |
|---|---|
| Gene Name | FSTL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 263 |
| Protein Names | Follistatin-related protein 3 (Follistatin-like protein 3) (Follistatin-related gene protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000070404 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O95633 |
| Gene Card | FSTL3 |
| Uniprot ID | O95633 |
| Pfam | PF09289; PF07648 |
| In ASD | no |
| Allosteric Prediction | no (-0.55561813) |
| Ortholog in Animals | Alpaca_ FSTL3 ( ortholog_one2one ) Dog_ FSTL3 ( ortholog_one2one ) GuineaPig_ FSTL3 ( ortholog_one2one ) Mouse_ Fstl3 ( ortholog_one2one ) Pig_ FSTL3 ( ortholog_one2one ) Rat_ Fstl3 ( ortholog_one2one ) |
| Ohnologs | FST |
| Paralogs | SPINK6, FSTL1, FSTL5, SPINK5, FSTL4, FST |
| Tissue | NA |
| Tissue Specificity | Expressed in a wide range of tissues. {ECO:0000269|PubMed:11459787}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2KCX (NMR - ) 3B4V (X-ray 2.48A ) 3SEK (X-ray 2.40A ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Secreted.; [Isoform 2]: Nucleus. Note=Although alternative initiation has been demonstrated and resulted in different localization, the major source of nuclear FSTL3 appears not to depend on translation initiation at Met-27 according to. {ECO:0000269|PubMed:16150905}. |
| Mouse PG classification | NA |
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