| Gene Information | |
|---|---|
| Gene Name | SCP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 547 |
| Protein Names | Sterol carrier protein 2 (SCP-2) (Acetyl-CoA C-myristoyltransferase) (EC 2.3.1.155) (Non-specific lipid-transfer protein) (NSL-TP) (Propanoyl-CoA C-acyltransferase) (EC 2.3.1.176) (SCP-2/3-oxoacyl-CoA thiolase) (SCP-2/thiolase) (EC 2.3.1.16) (SCP-chi) (SCPX) (Sterol carrier protein X) (SCP-X) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000116171 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P22307 |
| Gene Card | SCP2 |
| Uniprot ID | P22307 |
| Pfam | PF02036; PF02803; PF00108 |
| In ASD | no |
| Allosteric Prediction | yes (0.189431137) |
| Ortholog in Animals | Alpaca_ SCP2 ( ortholog_one2one ) Dog_ SCP2 ( ortholog_one2one ) Macaque_ SCP2 ( ortholog_one2one ) Mouse_ Scp2 ( ortholog_one2one ) Rabbit_ SCP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SCP2D1 |
| Tissue | NA |
| Tissue Specificity | Liver, fibroblasts, and placenta. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1QND (NMR - ) 2C0L (X-ray 2.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform SCP2]: Peroxisome {ECO:0000250|UniProtKB:P32020}. Cytoplasm {ECO:0000269|PubMed:10706581, ECO:0000269|PubMed:17157249}. Mitochondrion {ECO:0000269|PubMed:17157249}. Endoplasmic reticulum {ECO:0000250|UniProtKB:P32020}. Mitochondrion {ECO:0000250|UniProtKB:P32020}.; [Isoform SCPx]: Peroxisome {ECO:0000250|UniProtKB:P11915}. |
| Mouse PG classification | LPG |
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