| Gene Information | |
|---|---|
| Gene Name | FSHB |
| Organism | Homo sapiens (Human) |
| Gene Length | 129 |
| Protein Names | Follitropin subunit beta (Follicle-stimulating hormone beta subunit) (FSH-B) (FSH-beta) (Follitropin beta chain) |
| Target Name | follicle stimulating hormone |
| Target Type | Clinical trial target |
| Gene Age | 680 ( ENSG00000131808 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P01225 |
| Gene Card | FSHB |
| Uniprot ID | P01225 |
| Pfam | PF00007 |
| In ASD | no |
| Allosteric Prediction | yes (0.094645478) |
| Ortholog in Animals | Alpaca_ FSHB ( ortholog_one2one ) Dog_ FSHB ( ortholog_one2one ) GuineaPig_ FSHB ( ortholog_one2one ) Macaque_ FSHB ( ortholog_one2one ) Mouse_ Fshb ( ortholog_one2one ) Pig_ FSHB ( ortholog_one2one ) Rat_ Fshb ( ortholog_one2one ) Rabbit_ FSHB ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPHB5, TSHB, CGB2, CGB1, CGB7, CGB5, CGB8, CGB3, LHB |
| Tissue | pituitary.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);0.200000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1FL7 (X-ray 3.00A ) 1XWD (X-ray 2.92A ) 4AY9 (X-ray 2.50A ) 4MQW (X-ray 2.90A ) |
| DBSNP | rs6170 rs5030776 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:2494176}. Note=Efficient secretion requires dimerization with CGA. {ECO:0000269|PubMed:2494176}. |
| Mouse PG classification | NA |
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