| Gene Information | |
|---|---|
| Gene Name | FSD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 496 |
| Protein Names | Fibronectin type III and SPRY domain-containing protein 1 (MID1-related protein 1) (Microtubule-associated protein GLFND) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105255 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BTV5 |
| Gene Card | FSD1 |
| Uniprot ID | Q9BTV5 |
| Pfam | PF00041; PF00622 |
| In ASD | no |
| Allosteric Prediction | no (-0.269189293) |
| Ortholog in Animals | Alpaca_ FSD1 ( ortholog_one2one ) Dog_ FSD1 ( ortholog_one2one ) GuineaPig_ FSD1 ( ortholog_one2one ) Macaque_ FSD1 ( ortholog_one2one ) Mouse_ Fsd1 ( ortholog_one2one ) Pig_ FSD1 ( ortholog_one2one ) Rat_ Fsd1 ( ortholog_one2one ) Rabbit_ FSD1 ( ortholog_one2one ) |
| Ohnologs | FSD1L, TRIM36, TRIM46, FSD2 |
| Paralogs | CMYA5, FSD1L, FSD2 |
| Tissue | brain, testis |
| Tissue Specificity | Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord. {ECO:0000269|PubMed:11267680, ECO:0000269|PubMed:12154070}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35139245 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associate with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle. |
| Mouse PG classification | NA |
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