| Gene Information | |
|---|---|
| Gene Name | HRNR |
| Organism | Homo sapiens (Human) |
| Gene Length | 2850 |
| Protein Names | Hornerin |
| Target Name | hornerin |
| Target Type | NA |
| Gene Age | 25 ( ENSG00000197915 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | NA |
| Gene Card | HRNR |
| Uniprot ID | Q86YZ3 |
| Pfam | PF01023 |
| In ASD | no |
| Allosteric Prediction | yes (0.238486071) |
| Ortholog in Animals | Alpaca_ HRNR ( ortholog_one2one ) Mouse_ Hrnr ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FLG2, RPTN, FLG |
| Tissue | NA |
| Tissue Specificity | Expressed in cornified epidermis, psoriatic and regenerating skin after wounding. Found in the upper granular layer and in the entire cornified layer of epidermis. {ECO:0000269|PubMed:15507446, ECO:0000269|PubMed:21282207}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11204937 rs57277761 rs12741518 rs7545406 rs6587649 rs6666097 rs6587648 rs6587647 rs41266134 rs7520249 rs6662450 rs78949172 rs6659183 |
| Subcellular location [CC] | Cytoplasmic granule {ECO:0000269|PubMed:21282207}. Note=Found in keratohyalin granules in the granular cells of the epidermis. |
| Mouse PG classification | NA |
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