| Gene Information | |
|---|---|
| Gene Name | IFFO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 559 |
| Protein Names | Non-homologous end joining factor IFFO1 (NHEJ factor IFFO1) (Intermediate filament family orphan 1) (Tumor antigen HOM-TES-103) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000010295 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q0D2I5 |
| Gene Card | IFFO1 |
| Uniprot ID | Q0D2I5 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.929490781) |
| Ortholog in Animals | Alpaca_ IFFO1 ( ortholog_one2one ) Dog_ IFFO1 ( ortholog_one2one ) GuineaPig_ IFFO1 ( ortholog_one2one ) Macaque_ IFFO1 ( ortholog_one2one ) Mouse_ Iffo1 ( ortholog_one2one ) Pig_ IFFO1 ( ortholog_one2one ) Rat_ Iffo1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IFFO2 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12032826}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ABO (X-ray 2.65A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:31548606}. Nucleus, nucleoplasm {ECO:0000269|PubMed:31548606}. Nucleus inner membrane {ECO:0000269|PubMed:31548606}. Nucleus matrix {ECO:0000269|PubMed:31548606}. Note=Mainly soluble, the remaining is localized in the nuclear matrix (PubMed:31548606). Localized at double-strand break (DSB) sites near the lamina and nuclear matrix structures (PubMed:31548606). {ECO:0000269|PubMed:31548606}. |
| Mouse PG classification | NA |
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