| Gene Information | |
|---|---|
| Gene Name | ROMO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 79 |
| Protein Names | Reactive oxygen species modulator 1 (ROS modulator 1) (Epididymis tissue protein Li 175) (Glyrichin) (Mitochondrial targeting GxxxG motif protein) (MTGM) (Protein MGR2 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000125995 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P60602 |
| Gene Card | ROMO1 |
| Uniprot ID | P60602 |
| Pfam | PF10247 |
| In ASD | no |
| Allosteric Prediction | no (-1.260686295) |
| Ortholog in Animals | Alpaca_ ROMO1 ( ortholog_one2one ) Alpaca_ ROMO1 ( ortholog_one2many ) Dog_ ROMO1 ( ortholog_one2one ) GuineaPig_ ROMO1 ( ortholog_one2one ) Macaque_ ROMO1 ( ortholog_one2one ) Mouse_ Romo1 ( ortholog_one2one ) Pig_ ROMO1 ( ortholog_one2one ) Rat_ Romo1 ( ortholog_one2one ) Rabbit_ ROMO1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line. Highly expressed in brain tumors. {ECO:0000269|PubMed:16842742, ECO:0000269|PubMed:19535734}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.002240(Rat);0.036364(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1044521 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:16842742, ECO:0000269|PubMed:19535734}; Single-pass membrane protein {ECO:0000269|PubMed:16842742, ECO:0000269|PubMed:19535734}. |
| Mouse PG classification | NA |
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