Gene Information
Gene NameFRMD3
OrganismHomo sapiens (Human)
Gene Length597
Protein NamesFERM domain-containing protein 3 (Band 4.1-like protein 4O) (Ovary type protein 4.1) (4.1O)
Target NameNA
Target TypeNA
Gene Age680 ( ENSG00000172159 )
Evolutionary StageOpisthokonta
AlphaFoldDBA2A2Y4
Gene CardFRMD3
Uniprot IDA2A2Y4
PfamPF08736; PF09380; PF00373; PF09379
In ASDno
Allosteric Predictionno (-1.066114425)
Ortholog in AnimalsAlpaca_ FRMD3 ( ortholog_one2one )
Dog_ FRMD3 ( ortholog_one2one )
GuineaPig_ FRMD3 ( ortholog_one2one )
Macaque_ FRMD3 ( ortholog_one2one )
Mouse_ Frmd3 ( ortholog_one2one )
Pig_ FRMD3 ( ortholog_one2one )
Rat_ Frmd3 ( ortholog_one2one )
Rabbit_ FRMD3 ( ortholog_one2one )
OhnologsFRMD5
ParalogsEPB41L2, EPB41, EPB41L5, FRMD6, FRMD5, EPB41L4B, EPB41L4A, MYLIP, EPB41L3, EPB41L1
TissueNA
Tissue SpecificityOvary-specific. {ECO:0000269|PubMed:12601556}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs4877747 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass membrane protein {ECO:0000305}.
Mouse PG classificationNA
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