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Gene Information
Gene Name
FPS
Organism
Homo sapiens (Human)
Gene Length
419
Protein Names
Farnesyl pyrophosphate synthase (FPP synthase) (FPS) (EC 2.5.1.10) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (EC 2.5.1.1) (Farnesyl diphosphate synthase) (Geranyltranstransferase)
Target Name
NA
Target Type
NA
Gene Age
NA
Evolutionary Stage
NA
AlphaFoldDB
P14324
Gene Card
FDPS
Uniprot ID
P14324
Pfam
PF00348
In ASD
yes
Allosteric Prediction
NA
Ortholog in Animals
NA
Ohnologs
NA
Paralogs
NA
Tissue
NA
Tissue Specificity
NA
Pharmacological Animal Models
NA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
1YQ7
(X-ray
2.20A
)
1YV5
(X-ray
2.00A
)
1ZW5
(X-ray
2.30A
)
2F7M
(X-ray
2.30A
)
2F89
(X-ray
2.60A
)
2F8C
(X-ray
2.20A
)
2F8Z
(X-ray
2.60A
)
2F92
(X-ray
2.15A
)
2F94
(X-ray
1.94A
)
2F9K
(X-ray
2.06A
)
2OPM
(X-ray
2.40A
)
2OPN
(X-ray
2.70A
)
2QIS
(X-ray
1.80A
)
2RAH
(X-ray
2.00A
)
2VF6
(X-ray
2.10A
)
3B7L
(X-ray
1.95A
)
3CP6
(X-ray
1.95A
)
3N1V
(X-ray
2.18A
)
3N1W
(X-ray
2.56A
)
3N3L
(X-ray
2.74A
)
3N45
(X-ray
1.88A
)
3N46
(X-ray
2.35A
)
3N49
(X-ray
2.50A
)
3N5H
(X-ray
2.20A
)
3N5J
(X-ray
2.35A
)
3N6K
(X-ray
2.25A
)
3RYE
(X-ray
2.10A
)
3S4J
(X-ray
1.95A
)
4DEM
(X-ray
1.85A
)
4GA3
(X-ray
2.39A
)
4H5C
(X-ray
2.02A
)
4H5D
(X-ray
2.02A
)
4H5E
(X-ray
2.04A
)
4JVJ
(X-ray
2.80A
)
4KFA
(X-ray
1.98A
)
4KPD
(X-ray
1.96A
)
4KPJ
(X-ray
1.95A
)
4KQ5
(X-ray
2.40A
)
4KQS
(X-ray
1.97A
)
4KQU
(X-ray
2.07A
)
4L2X
(X-ray
2.55A
)
4LFV
(X-ray
2.00A
)
4LPG
(X-ray
2.35A
)
4LPH
(X-ray
2.30A
)
4N1Z
(X-ray
2.35A
)
4N9U
(X-ray
2.11A
)
4NFI
(X-ray
1.85A
)
4NFJ
(X-ray
2.05A
)
4NFK
(X-ray
1.85A
)
4NG6
(X-ray
2.35A
)
4NKE
(X-ray
1.46A
)
4NKF
(X-ray
2.00A
)
4NUA
(X-ray
1.43A
)
4OGU
(X-ray
2.10A
)
4P0V
(X-ray
2.40A
)
4P0W
(X-ray
2.41A
)
4P0X
(X-ray
2.50A
)
4PVX
(X-ray
2.18A
)
4PVY
(X-ray
2.05A
)
4Q23
(X-ray
1.98A
)
4QPF
(X-ray
1.59A
)
4QXS
(X-ray
1.90A
)
4RXA
(X-ray
2.20A
)
4XQR
(X-ray
2.15A
)
4XQS
(X-ray
2.30A
)
4XQT
(X-ray
2.10A
)
5CG5
(Other
1.40A
)
5CG6
(Other
1.70A
)
5DGM
(X-ray
2.86A
)
5DGN
(X-ray
2.08A
)
5DGS
(X-ray
2.62A
)
5DIQ
(X-ray
2.10A
)
5DJP
(X-ray
2.40A
)
5DJR
(X-ray
2.40A
)
5DJV
(X-ray
2.30A
)
5JA0
(X-ray
1.90A
)
5JUZ
(X-ray
2.40A
)
5JV0
(X-ray
2.40A
)
5JV1
(X-ray
2.30A
)
5JV2
(X-ray
2.30A
)
5KSX
(X-ray
2.65A
)
5YGI
(X-ray
2.18A
)
6N7Y
(X-ray
2.00A
)
6N7Z
(X-ray
2.55A
)
6N82
(X-ray
2.00A
)
6N83
(X-ray
2.00A
)
6OAG
(X-ray
2.30A
)
6OAH
(X-ray
2.20A
)
DBSNP
rs863225241
rs41314549
rs17456
Subcellular location [CC]
Cytoplasm.
Mouse PG classification
NA
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