| Gene Information | |
|---|---|
| Gene Name | FAAP10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 81 |
| Protein Names | Centromere protein X (CENP-X) (FANCM-associated histone fold protein 2) (FANCM-interacting histone fold protein 2) (Fanconi anemia-associated polypeptide of 10 kDa) (Retinoic acid-inducible gene D9 protein homolog) (Stimulated by retinoic acid gene 13 protein homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | A8MT69 |
| Gene Card | CENPX |
| Uniprot ID | A8MT69 |
| Pfam | PF09415 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.082877(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4DRA (X-ray 2.41A ) 4DRB (X-ray 2.63A ) 4E44 (X-ray 2.10A ) 4E45 (X-ray 2.00A ) 4NDY (X-ray 7.00A ) 4NE1 (X-ray 6.50A ) 4NE3 (X-ray 1.80A ) 4NE5 (X-ray 2.50A ) 4NE6 (X-ray 2.10A ) 7R5S (EM 2.83A ) 7YWX (EM 12.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19620631, ECO:0000269|PubMed:24522885}. Chromosome, centromere {ECO:0000269|PubMed:19620631, ECO:0000269|PubMed:24522885}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:19620631, ECO:0000269|PubMed:24522885}. Note=Assembly of CENPS and CENPX and its partner subunits CENPT and CENPW at centromeres occurs through a dynamic exchange mechanism. Although exchange is continuous in the cell cycle, de novo assembly starts principally during mid-late S phase and is complete by G2. CENPX being less stably bound at the kinetochore than CENPS. {ECO:0000269|PubMed:19620631, ECO:0000269|PubMed:24522885}. |
| Mouse PG classification | NA |
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