| Gene Information | |
|---|---|
| Gene Name | MBIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 344 |
| Protein Names | MAP3K12-binding inhibitory protein 1 (MAPK upstream kinase-binding inhibitory protein) (MUK-binding inhibitory protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000151332 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NS73 |
| Gene Card | MBIP |
| Uniprot ID | Q9NS73 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.075685386) |
| Ortholog in Animals | Alpaca_ MBIP ( ortholog_one2one ) Dog_ MBIP ( ortholog_one2one ) GuineaPig_ MBIP ( ortholog_one2one ) Macaque_ MBIP ( ortholog_one2one ) Mouse_ Mbip ( ortholog_one2one ) Pig_ MBIP ( ortholog_one2one ) Rat_ Mbip ( ortholog_one2one ) Rabbit_ MBIP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NMRK2, MOCS2, NMRK1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. High expression seen in the heart and lung. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.038059(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2899849 rs3168891 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Note=Shows a cytoplasmic localization when coexpressed with MAP3K12. |
| Mouse PG classification | NA |
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