| Gene Information | |
|---|---|
| Gene Name | SERPING1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 500 |
| Protein Names | Plasma protease C1 inhibitor (C1 Inh) (C1Inh) (C1 esterase inhibitor) (C1-inhibiting factor) (Serpin G1) |
| Target Name | plasma protease c1 inhibitor |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000149131 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P05155 |
| Gene Card | SERPING1 |
| Uniprot ID | P05155 |
| Pfam | PF00079 |
| In ASD | yes |
| Allosteric Prediction | yes (0.736191189) |
| Ortholog in Animals | Alpaca_ SERPING1 ( ortholog_one2one ) Dog_ SERPING1 ( ortholog_one2one ) GuineaPig_ SERPING1 ( ortholog_one2one ) Macaque_ SERPING1 ( ortholog_one2one ) Mouse_ Serping1 ( ortholog_one2one ) Pig_ SERPING1 ( ortholog_one2one ) Rat_ Serping1 ( ortholog_one2one ) Rabbit_ SERPING1 ( ortholog_one2one ) |
| Ohnologs | SERPINF1 |
| Paralogs | SERPINB7, SERPINF1, SERPINI1, AGT, SERPIND1, SERPINA7, SERPINB8, SERPINA6, SERPINI2, HMSD, SERPINB6, SERPINC1, SERPINB1, SERPINA10, SERPINH1, SERPINB13, SERPINA3, SERPINA5, SERPINA9, SERPINA12, SERPINE1, SERPINF2, SERPINA4, SERPINB11, SERPINB5, SERPINB12, SERPINB9, SERPINE3, SERPINB4, SERPINB3, SERPINE2, SERPINA1, SERPINA2, SERPINB10, SERPINA11, SERPINB2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OAY (X-ray 2.35A ) 5DU3 (X-ray 2.10A ) 5DUQ (X-ray 2.90A ) 7AKV (EM 3.60A ) |
| DBSNP | rs11229062 rs11546660 rs200534715 rs281875168 rs281875169 rs281875170 rs281875171 rs281875172 rs281875173 rs1803212 rs281875174 rs281875175 rs281875176 rs121907949 rs121907947 rs121907950 rs28940870 rs121907948 rs121907948 rs28940870 rs281875177 rs4926 rs281875178 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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