| Gene Information | |
|---|---|
| Gene Name | ADSS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 456 |
| Protein Names | Adenylosuccinate synthetase isozyme 2 (AMPSase 2) (AdSS 2) (EC 6.3.4.4) (Adenylosuccinate synthetase, acidic isozyme) (Adenylosuccinate synthetase, liver isozyme) (L-type adenylosuccinate synthetase) (IMP--aspartate ligase 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000035687 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P30520 |
| Gene Card | ADSS2 |
| Uniprot ID | P30520 |
| Pfam | PF00709 |
| In ASD | no |
| Allosteric Prediction | yes (0.770333805) |
| Ortholog in Animals | Alpaca_ ADSS2 ( ortholog_one2one ) Dog_ ADSS2 ( ortholog_one2one ) GuineaPig_ ADSS2 ( ortholog_one2one ) Macaque_ ADSS2 ( ortholog_one2one ) Mouse_ Adss ( ortholog_one2one ) Pig_ ADSS2 ( ortholog_one2one ) Rat_ Adss ( ortholog_one2one ) Rabbit_ ADSS2 ( ortholog_one2one ) |
| Ohnologs | ADSS1 |
| Paralogs | ADSS1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004680(Rat);0.027088(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2V40 (X-ray 1.90A ) |
| DBSNP | rs12134870 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03127}. Mitochondrion {ECO:0000250|UniProtKB:A4Z6H1}. Note=Partially associated with particulate fractions. |
| Mouse PG classification | NA |
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