| Gene Information | |
|---|---|
| Gene Name | LAMTOR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 125 |
| Protein Names | Ragulator complex protein LAMTOR2 (Endosomal adaptor protein p14) (Late endosomal/lysosomal Mp1-interacting protein) (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2) (Mitogen-activated protein-binding protein-interacting protein) (MAPBP-interacting protein) (Roadblock domain-containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000116586 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y2Q5 |
| Gene Card | LAMTOR2 |
| Uniprot ID | Q9Y2Q5 |
| Pfam | PF03259 |
| In ASD | no |
| Allosteric Prediction | no (-0.315515526) |
| Ortholog in Animals | Alpaca_ LAMTOR2 ( ortholog_one2many ) Dog_ LAMTOR2 ( ortholog_one2one ) GuineaPig_ LAMTOR2 ( ortholog_one2one ) Macaque_ LAMTOR2 ( ortholog_one2one ) Mouse_ Lamtor2 ( ortholog_one2one ) Pig_ LAMTOR2 ( ortholog_one2one ) Rat_ Lamtor2 ( ortholog_one2many ) Rabbit_ LAMTOR2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.117647(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5X6U (X-ray 2.40A ) 5X6V (X-ray 2.02A ) 5Y39 (X-ray 2.65A ) 5Y3A (X-ray 2.90A ) 6B9X (X-ray 1.42A ) 6EHP (X-ray 2.30A ) 6EHR (X-ray 2.90A ) 6NZD (EM 3.60A ) 6U62 (EM 3.18A ) 6ULG (EM 3.31A ) 6WJ2 (EM 3.20A ) 6WJ3 (EM 3.90A ) 7T3A (EM 4.00A ) 7T3B (EM 3.90A ) 7T3C (EM 4.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Lysosome membrane {ECO:0000269|PubMed:17897319}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
| Mouse PG classification | LPG |
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