| Gene Information | |
|---|---|
| Gene Name | RAD54B |
| Organism | Homo sapiens (Human) |
| Gene Length | 910 |
| Protein Names | DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000197275 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9Y620 |
| Gene Card | RAD54B |
| Uniprot ID | Q9Y620 |
| Pfam | PF00271; PF00176 |
| In ASD | no |
| Allosteric Prediction | no (-1.009879492) |
| Ortholog in Animals | Alpaca_ RAD54B ( ortholog_one2one ) Dog_ RAD54B ( ortholog_one2one ) GuineaPig_ RAD54B ( ortholog_one2one ) Macaque_ RAD54B ( ortholog_one2one ) Mouse_ Rad54b ( ortholog_one2one ) Pig_ RAD54B ( ortholog_one2one ) Rat_ Rad54b ( ortholog_one2one ) Rabbit_ RAD54B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SMARCA1, HLTF, HELLS, SHPRH, BTAF1, ZRANB3, SMARCA5, TTF2, SMARCA2, CHD9, SMARCAL1, CHD1L, CHD3, RAD54L2, SMARCAD1, CHD4, ATRX, INO80, CHD6, SRCAP, CHD1, CHD2, RAD54L, CHD7, CHD8, EP400, ERCC6, ERCC6L, CHD5, SMARCA4 |
| Tissue | substantia.nigra |
| Tissue Specificity | Abundantly expressed in testis and spleen. Relatively low levels observed in thymus, prostate, ovary and colon. {ECO:0000269|PubMed:10362364}. |
| Pharmacological Animal Models | 0.023894(Chimpanzee);0.150968(Mouse);NULL(Rat);0.104495(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28910279 rs2919661 rs119490107 rs114216685 rs752511501 rs150017319 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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