| Gene Information | |
|---|---|
| Gene Name | FNDC4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 234 |
| Protein Names | Fibronectin type III domain-containing protein 4 (Fibronectin type III repeat-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000115226 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9H6D8 |
| Gene Card | FNDC4 |
| Uniprot ID | Q9H6D8 |
| Pfam | PF00041 |
| In ASD | no |
| Allosteric Prediction | no (-1.787947025) |
| Ortholog in Animals | Alpaca_ FNDC4 ( ortholog_one2one ) Dog_ FNDC4 ( ortholog_one2one ) GuineaPig_ FNDC4 ( ortholog_one2one ) Macaque_ FNDC4 ( ortholog_one2one ) Mouse_ Fndc4 ( ortholog_one2one ) Pig_ FNDC4 ( ortholog_one2one ) Rat_ AABR07063279.1 ( ortholog_one2one ) Rabbit_ FNDC4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FNDC5 |
| Tissue | NA |
| Tissue Specificity | Up-regulated in colon cells of patients with inflammatory bowel disease (IBD). {ECO:0000269|PubMed:27066907}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Secreted {ECO:0000250|UniProtKB:Q3TR08}. Note=The N-terminus is probably cleaved to release a secreted extracellular portion of the protein. {ECO:0000250|UniProtKB:Q3TR08}. |
| Mouse PG classification | NA |
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