| Gene Information | |
|---|---|
| Gene Name | GPR135 |
| Organism | Homo sapiens (Human) |
| Gene Length | 494 |
| Protein Names | G-protein coupled receptor 135 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000181619 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IZ08 |
| Gene Card | GPR135 |
| Uniprot ID | Q8IZ08 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-1.168270735) |
| Ortholog in Animals | Alpaca_ GPR135 ( ortholog_one2one ) Dog_ GPR135 ( ortholog_one2one ) Mouse_ Gpr135 ( ortholog_one2one ) Pig_ GPR135 ( ortholog_one2one ) Rat_ Gpr135 ( ortholog_one2one ) Rabbit_ GPR135 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPR62, GPR61, GPR176 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1752428 rs1752427 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:28827538}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:28827538}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome. {ECO:0000269|PubMed:28827538}. |
| Mouse PG classification | NA |
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