| Gene Information | |
|---|---|
| Gene Name | PYDC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 97 |
| Protein Names | Pyrin domain-containing protein 2 (Pyrin-only protein 2) (cellular POP2) (cPOP2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000253548 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q56P42 |
| Gene Card | PYDC2 |
| Uniprot ID | Q56P42 |
| Pfam | PF02758 |
| In ASD | no |
| Allosteric Prediction | no (-0.801506147) |
| Ortholog in Animals | Alpaca_ PYDC2 ( ortholog_one2many ) Macaque_ PYDC2 ( ortholog_one2one ) Mouse_ Nlrp2 ( ortholog_one2many ) Rat_ Nlrp2 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NLRP2, NLRP9, NLRC5, NLRP14, NLRP7, NLRP4, CIITA, NOD1, NLRP8, NLRP10, NLRP3, NLRP5, NLRP6, NLRP11, NLRC3, NLRX1, NLRP12, NLRP13, NLRP1, NOD2 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in peripheral blood. Weakly expressed in testis. {ECO:0000269|PubMed:17339483}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs293833 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17178784, ECO:0000269|PubMed:17339483}. Nucleus {ECO:0000269|PubMed:17178784, ECO:0000269|PubMed:17339483}. Note=Recruited to specks formed by PYCARD within the cytoplasm. {ECO:0000269|PubMed:17178784}. |
| Mouse PG classification | NA |
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