| Gene Information | |
|---|---|
| Gene Name | FMS |
| Organism | Homo sapiens (Human) |
| Gene Length | 972 |
| Protein Names | Macrophage colony-stimulating factor 1 receptor (CSF-1 receptor) (CSF-1-R) (CSF-1R) (M-CSF-R) (EC 2.7.10.1) (Proto-oncogene c-Fms) (CD antigen CD115) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P07333 |
| Gene Card | CSF1R |
| Uniprot ID | P07333 |
| Pfam | PF00047; PF07714 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in bone marrow and in differentiated blood mononuclear cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2I0V (X-ray 2.80A ) 2I0Y (X-ray 1.90A ) 2I1M (X-ray 1.80A ) 2OGV (X-ray 2.70A ) 3BEA (X-ray 2.02A ) 3DPK (X-ray 1.95A ) 3KRJ (X-ray 2.10A ) 3KRL (X-ray 2.40A ) 3LCD (X-ray 2.50A ) 3LCO (X-ray 3.40A ) 4DKD (X-ray 3.00A ) 4HW7 (X-ray 2.90A ) 4LIQ (X-ray 2.60A ) 4R7H (X-ray 2.80A ) 4R7I (X-ray 2.75A ) 4WRL (X-ray 2.80A ) 4WRM (X-ray 6.85A ) 6IG8 (X-ray 1.80A ) 6N33 (X-ray 2.25A ) 6T2W (X-ray 1.70A ) 6WXJ (X-ray 2.62A ) 7MFC (X-ray 2.80A ) |
| DBSNP | rs56048668 rs1351319114 rs41338945 rs3829986 rs10079250 rs34951517 rs917027829 rs55942044 rs281860268 rs1554101963 rs281860269 rs184499252 rs690016559 rs201569135 rs41355444 rs690016566 rs281860270 rs281860271 rs281860273 rs587777247 rs281860281 rs281860274 rs387906662 rs690016558 rs281860277 rs281860278 rs281860279 rs281860280 rs690016560 rs34030164 rs56059682 rs1801271 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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