| Gene Information | |
|---|---|
| Gene Name | FMO3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 532 |
| Protein Names | Flavin-containing monooxygenase 3 (EC 1.14.13.148) (EC 1.14.13.32) (EC 1.14.13.8) (Dimethylaniline monooxygenase [N-oxide-forming] 3) (Dimethylaniline oxidase 3) (FMO II) (FMO form 2) (Hepatic flavin-containing monooxygenase 3) (FMO 3) (Trimethylamine monooxygenase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000007933 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P31513 |
| Gene Card | FMO3 |
| Uniprot ID | P31513 |
| Pfam | PF00743 |
| In ASD | no |
| Allosteric Prediction | yes (0.105779343) |
| Ortholog in Animals | Alpaca_ FMO3 ( ortholog_one2one ) Dog_ FMO3 ( ortholog_one2one ) GuineaPig_ FMO3 ( ortholog_one2one ) Macaque_ FMO3 ( ortholog_one2one ) Mouse_ Fmo3 ( ortholog_one2one ) Pig_ FMO3 ( ortholog_one2one ) Rat_ Fmo3 ( ortholog_one2one ) Rabbit_ FMO3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FMO5, FMO2, FMO4, FOXRED2, FMO1 |
| Tissue | liver |
| Tissue Specificity | Liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs72549320 rs72549321 rs72549322 rs72549323 rs12072582 rs72549326 rs2266782 rs529940450 rs28363549 rs1736557 rs2066530 rs2266780 rs28363581 rs2066532 rs72549331 rs774785217 rs72549332 rs72549334 rs72549335 |
| Subcellular location [CC] | Microsome membrane {ECO:0000250|UniProtKB:P32417}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P32417}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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