| Gene Information | |
|---|---|
| Gene Name | FMO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 535 |
| Protein Names | Flavin-containing monooxygenase 2 (EC 1.14.13.-) (Dimethylaniline oxidase 2) (FMO 1B1) (Pulmonary flavin-containing monooxygenase 2) (FMO 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000094963 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q99518 |
| Gene Card | FMO2 |
| Uniprot ID | Q99518 |
| Pfam | PF00743 |
| In ASD | no |
| Allosteric Prediction | no (-0.098744023) |
| Ortholog in Animals | Alpaca_ FMO2 ( ortholog_one2one ) Dog_ FMO2 ( ortholog_one2one ) GuineaPig_ FMO2 ( ortholog_one2one ) Macaque_ FMO2 ( ortholog_one2one ) Mouse_ Fmo2 ( ortholog_one2one ) Pig_ FMO2 ( ortholog_one2one ) Rat_ Fmo2 ( ortholog_one2one ) Rabbit_ FMO2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FMO5, FMO3, FMO4, FOXRED2, FMO1 |
| Tissue | NA |
| Tissue Specificity | Expressed in lung (at protein level). Expressed predominantly in lung, and at a much lesser extent in kidney. Also expressed in fetal lung, but not in liver, kidney and brain. {ECO:0000269|PubMed:11042094, ECO:0000269|PubMed:9804831}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2020870 rs55708639 rs28745274 rs2020860 rs2307492 rs2020862 rs28369895 rs2020863 rs28369899 rs2020865 |
| Subcellular location [CC] | Microsome membrane {ECO:0000250|UniProtKB:P17635}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P17635}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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