| Gene Information | |
|---|---|
| Gene Name | FMO2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 558 |
| Protein Names | Dimethylaniline monooxygenase [N-oxide-forming] 4 (EC 1.14.13.8) (Dimethylaniline oxidase 4) (Hepatic flavin-containing monooxygenase 4) (FMO 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000094963 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P31512 |
| Gene Card | FMO4 |
| Uniprot ID | P31512 |
| Pfam | PF00743 |
| In ASD | no |
| Allosteric Prediction | no (-0.098744023) |
| Ortholog in Animals | Alpaca_ FMO2 ( ortholog_one2one ) Dog_ FMO2 ( ortholog_one2one ) GuineaPig_ FMO2 ( ortholog_one2one ) Macaque_ FMO2 ( ortholog_one2one ) Mouse_ Fmo2 ( ortholog_one2one ) Pig_ FMO2 ( ortholog_one2one ) Rat_ Fmo2 ( ortholog_one2one ) Rabbit_ FMO2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FMO5, FMO3, FMO4, FOXRED2, FMO1 |
| Tissue | NA |
| Tissue Specificity | Liver. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs866374389 rs72549338 rs3737925 rs1042767 rs61342270 rs45599742 rs45487792 rs45528740 |
| Subcellular location [CC] | Microsome membrane {ECO:0000250|UniProtKB:Q8K4B7}; Single-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q8K4B7}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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