| Gene Information | |
|---|---|
| Gene Name | FMO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 532 |
| Protein Names | Flavin-containing monooxygenase 1 (EC 1.14.13.148) (EC 1.14.13.8) (Dimethylaniline monooxygenase [N-oxide-forming] 1) (Dimethylaniline oxidase 1) (Fetal hepatic flavin-containing monooxygenase 1) (FMO 1) (Trimethylamine monooxygenase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000010932 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q01740 |
| Gene Card | FMO1 |
| Uniprot ID | Q01740 |
| Pfam | PF00743 |
| In ASD | no |
| Allosteric Prediction | no (-0.079737595) |
| Ortholog in Animals | Alpaca_ FMO1 ( ortholog_one2one ) Dog_ FMO1 ( ortholog_one2one ) GuineaPig_ FMO1 ( ortholog_one2one ) Macaque_ FMO1 ( ortholog_one2one ) Mouse_ Fmo1 ( ortholog_one2one ) Pig_ FMO1 ( ortholog_one2one ) Rat_ Fmo1 ( ortholog_one2one ) Rabbit_ FMO1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FMO5, FMO3, FMO2, FMO4, FOXRED2 |
| Tissue | kidney |
| Tissue Specificity | Expressed mainly in fetal and adult liver. {ECO:0000269|PubMed:1712018}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs56841822 rs16864310 rs28360418 rs16864314 rs28360419 rs28360420 rs28360421 rs28360433 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P36365}; Single-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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